MEDPLUS PHARMA

Oxycontin is a prescription medicine used to treat moderate to severe pain. Oxycontin may be used alone or with other medications.Oxycontin is an opioid pain medication.It is not known if Oxycontin is safe and effective in children younger than 18 years of age.

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Drug Introduction

Buy Oxycontin Online- Oxycontin is the extended-release formulation of oxycodone. It is an opioid agonist available in 10 mg, 15 mg, 20 mg, 30 mg, 40 mg, 60 mg, and 80 mg of oxycodone hydrochloride for oral administration. Oxycodone is a derivation from thebaine, an opium alkaloid.

Oxycontin tablets also contain inactive ingredients including Hypromellose, butylated hydroxytoluene (BHT), polyethylene oxide, polyethylene glycol 400, titanium dioxide, and magnesium stearate. Additionally, 10 mg tablets also contain hydroxypropyl cellulose, 15 mg contain yellow iron oxide, black iron oxide, and red iron oxide, 20 mg contain red iron oxide and polysorbate, 30 mg contain red iron oxide, black iron oxide, yellow iron oxide, and polysorbate 80, 40 mg contain yellow iron oxide and polysorbate 80, 60 mg contain black iron oxide, red iron oxide, and polysorbate 80, and 80 mg contain yellow iron oxide, hydroxypropyl cellulose, indigo carmine aluminum lake, and FD & C Blue No. #2.

Oxycontin is only for patients who need continuous long-term pain medication. It is not for an “as needed” or prn analgesic use.

Licit Uses of Oxycontin

Buy oxycontin online for the management of severe pain that requires around-the-clock, daily, long-duration opioid treatment and for which other treatment alternatives are inadequate or insufficient.

FDA approved oxycontin for adults and opioid-tolerant pediatric patients of 11 years or above who are already taking and tolerate a minimum daily opioid (oxycodone or it’s equivalent) dosage of at least 20 mg orally.

As oxycontin is an extended-release opioid medication, it has a higher risk of addiction, abuse, and misuse, even at recommended doses. It also has more significant risks of overdose and deaths. Due to these risk factors, doctors recommend oxycontin only to those patients for whom other alternative treatment options such as non-opioid analgesics or immediate-release opioids are not tolerated, ineffective, or would be inadequate to provide required analgesic effects.

Illicit Uses of Oxycontin

Recent studies show an increase in the non-medical uses of oxycontin in the United States. In a school survey of 7726 students from grade 7 to 12, over 1.3% of students reported continuous use of oxycontin, and 1% of students reported use of the drug in the past year. Similar studies demonstrate that over 49% of the adolescent abusers buy oxycontin online for its euphoric effects.

Chemistry

Oxycontin contains oxycodone which derives its chemical name from codeine due to the similarities in the part of their chemical structure from the following differences:

• Oxycodone has a hydroxy group attached at carbon-14 while codeine has hydrogen at its place

• Oxycodone has a 7,8-dihydro property while codeine has a double bond between these carbons, and

• Like ketones, oxycodone has a carbonyl group attached in place of hydroxyl group as in codeine

Oxycodone is also similar to hydrocodone, the only difference being that it has a hydroxyl group attached at carbon-14.

Manufacturers market oxycodone as various salts, most common of them is hydrochloride salt. The free base conversion ratios of different oxycodone salts are as following:

• Hydrochloride: 0.896

• Bitartrate: 0.667

• Tartrate: 0.750

• Camphosulfonate: 0.567

• Pectinate: 0.588

• Phenylpropionate: 0.678

• Sulfate: 0.887

• Phosphate: 0.763

• Terephthalate: 0.792

The hydrochloride salt is the base of most oxycodone products in the United States.

 

Side Effects of Oxycontin

The most common unwanted reactions occurred due to oxycontin include:

• Nausea

• Constipation

• Somnolence

• Pruritus

• Dizziness

• Headache

• Vomiting

• Sweating

• Asthenia

Other adverse effects of oxycontin include:

Gastrointestinal disorders: diarrhea, abdominal pain, gastritis, dyspepsia

General conditions: fever, chills

Metabolic disorder: anorexia

Musculoskeletal disorder: muscle twitching

Psychiatric disorder: anxiety, abnormal dreams, dysphoria, confusion, insomnia, euphoria, unusual thoughts, nervousness

Respiratory disease: hiccups, dyspnea

Skin conditions: rash

Vascular disease: postural hypotension

Ear condition: tinnitus

Eye disorder: abnormal vision

Gastrointestinal diseases: eructation, increased appetite, stomatitis, dysphagia

General disease: edema, withdrawal symptoms, thirst, malaise, facial edema, chest pain

Oxycontin may increase the risks of severe reactions such as respiratory depression, respiratory arrest, apnea, hypotension, circulatory depression, or shock.